Medical image registration is a difficult problem. Not only a registrationalgorithm needs to capture both large and small scale image deformations, italso has to deal with global and local image intensity variations. In thispaper we describe a new multiresolution elastic image registration method thatchallenges these difficulties in image registration. To capture large and smallscale image deformations, we use both global and local affine transformationalgorithms. To address global and local image intensity variations, we apply animage intensity standardization algorithm to correct image intensityvariations. This transforms image intensities into a standard intensity scale,which allows highly accurate registration of medical images.
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